49ers vs Commanders Player Props Picks: NFL Week 6

CERO MIEDO BAY BAY! Following a weekend of upsets in both College Football and the NFL, the 49ers will face off against the Commanders looking to avoid the UPSET BUG and stay undefeated this season.

The Commanders will be "fighting for the NFC East" tonight as the division is in shambles. The NFC East is a Commanders loss tonight from becoming the first division in NFL HISTORY to be winless in consecutive weeks in which all teams in the division played a game!

Easy to say both teams will need "zero fear" tonight for their own reasons, but without further ado, here are my 49ers vs Commanders player props picks.

Prop #1: Mike Evans Over 63.5 Receiving Yards (-112 Draft Kings)

God I hope Mike Evans plays in tonight game. I have a Fantasy Football matchup to win and need at least 19 points from him and the niners defense tonight!

#1 wide receivers have FEASTED off the Commanders defense this season. Four of their five games this season have seen at least one of their opponents' wide receivers hitting this yardage mark for the games. Out of those four games, three of them have seen the top wide receiver option record 100+ receiving yards in the game. Week 1 was the only game bucking this trend as Dontayvion Wicks had 73 receiving yards compared to DeVonta Smith's 53 receiving yards.

Yes, Evans has hit this line in only 40% of his games this season, but he's had 70+ receiving yards in each of his last two games. The only factors I see affecting this props are: 1) George Kittle and 2) the Commanders getting blown out.

Kittle is the only other threat in the receiving game I fear taking targets away from Evans, but still feel like both will get their fair share. For the blowout, I don't think one will happen, but it's possible. The Niners have played closer games in their last three games, compared to their first two games of the season. The Commanders have only been blown out one this season and that was overseas in London.

Prop #2: George Kittle Anytime Touchdown (+110 FanDuel/Draft Kings)

Mister, Cero Miedo himself! I really like George Kittle tonight against this Commanders team!

The Commanders are weak against the tight end position. It's a weakness I could see Brock Purdy and the Niners exploiting tonight. Opposing tight ends have been targeted a total of 36 times against Washington (7.2 targets per game). That's an average I could see Kittle reaching tonight! Outside of his first two games, he's had six or seven targets in each of his last three games.

Opposing tight ends have also been able to find the endzone in four of the Commanders' five games this season. On top of that, Eagles' Dallas Goedert, Cowboys' Jake Ferguson, and Giants' Isaiah Likely all have scored two touchdowns in one games against Washington. Kittle has only one game with two touchdowns this season, but two isn't out of the frame for arguably the best tight end in the NFL.

Kittle will get his targets tonight. He will be involved heavily in the offensive gameplan. He'll also get his looks in the rezone as well. I really like him to get one tonight.

Long Shot Prop: Mike Evans First Touchdown Scorer (+725 MGM)

When looking at the Commanders last three games, there's only three Niners on the list as candidates for First Touchdown Scorer. It's either Christian McCaffrey, Mike Evans, or George Kittle. Through five games, the Commanders' opponents first touchdown has come twice from the tight ends, twice from the wide receivers, and once from the running backs.

The only two with juicy odds for this prop from the Niners are Mike Evans and George Kittle. However, Evans might be the better choice based off 49ers games this season.

Wide receivers have scored the first touchdown in four of San Francisco's five games in 2026.Also, based on the receivers the 49ers will have tonight, Evans is the CLEAR top option in that position if he suits up.

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